Marco André Cardoso

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The brown seaweed Sargassum stenophyllum biosynthesizes two different sets of fucoidans. One of them is characterized by higher percentages of glucuronic acid and fewer sulfate groups, which are situated on different sugar units. alpha-L-Fucose was the major component but other sugars like beta-D-galactose, beta-D-mannose, alpha-D-glucuronic acid,(More)
The sulfated, methylated galactan isolated from the red seaweed Bostrychia montagnei, showed an unusually narrow structural dispersion. This agaran has the defining linear backbone of alternating 3-linked beta-D-galactopyranosyl units and 4-linked alpha-L-galactopyranosyl and 3,6-anhydrogalactopyranosyl residues. The D-units have C-6 methylation, C-6 single(More)
Cryptonemia seminervis biosynthesizes a family of D,L-hybrid galactans based on the classical 3-linked beta-D-galactopyranosyl-->4-linked alpha-D- and alpha-L-galactopyranosyl alternating sequence (A-units-->B-units) with major amounts of alpha-D- and alpha-L-galactose and 3,6-anhydro-D- and L-galactose and lesser percentages of(More)
Monitoring of the plasmatic levels of levodopa (LEV) and carbidopa (CAR) is necessary to adjust the dose of these drugs according to the individual needs of Parkinson's disease patients. To support drug therapeutic monitoring, a method using HILIC mode and LC-MS/MS was developed for the simultaneous determination of carbidopa, levodopa, and its metabolites(More)
Sulfated xylomannans were isolated from two species of genus Chondrophycus by aqueous extraction followed by KCl fractionation. Structural determination of the native, desulfated and Smith-degraded KCl-precipitated polysaccharides carried out by composition and methylation analysis and NMR spectroscopy (1D and 2D experiments) showed the following general(More)
The static gluon-quark-antiquark interaction is investigated using lattice QCD techniques. A Wil-son loop adequate to the static hybrid three-body system is developed and, using a 24 3 × 48 periodic lattice with β = 6.2, the potential energy of the system is measured for different geometries. For the medium range behaviour, when the quarks are far apart, we(More)
BACKGROUND In this study, we developed and validated a HPLC-MS/MS method capable of simultaneously determining levodopa, carbidopa, entacapone, tolcapone, 3-O-methyldopa and dopamine in human plasma. RESULTS & METHODOLOGY: Chromatographic separation was achieved using a C8 column with a mobile phase consisting of a gradient of water and(More)
We study tetraquark resonances with lattice QCD potentials computed for a static b̄b̄ pair in the presence of two lighter quarks ud, the Born-Oppenheimer approximation and the emergent wave method. As a proof of concept we focus on the system with isospin I = 0, but consider different relative angular momenta l of the heavy quarks b̄b̄. For l = 0 a bound(More)
Zebrafish early life stages (ELS) assays have been increasingly used to assess the toxicity of chemicals and waste waters, showing a great potential due to the wide variety of endpoints that can be incorporated in the test. Moreover, zebrafish ELS test have been proposed, mainly for ethical reasons, as a surrogate for tests with adults. In this work, the(More)
We utilize Polyakov loop correlations to study (3+1)D compact U (1) flux tubes and the static electron-positron potential in lattice gauge theory. By using field operators it is possible in U(1) lattice gauge theory to probe directly the electric and magnetic fields. In order to improve the signal-to-noise ratio in the confinement phase, we apply the(More)