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We have designed a novel, precise, and sensitive assay to measure unspliced (US) human immunodeficiency virus type 1 (HIV-1) mRNA in peripheral blood mononuclear cells of HIV-1-infected individuals by using real-time PCR and molecular beacons. Individuals were classified as either well suppressed (WS) or partially suppressed, based on longitudinal(More)
World wide crude transportation is the central logistics operation that links the upstream and downstream functions and plays a crucial role in the global supply chain management in the oil industry. In this work, we develop a decision support system to investigate and improve the combined inventory and transportation system in a representative worldwide(More)
BACKGROUND The TP53 pathway, in which TP53 and its negative regulator MDM2 are the central elements, has an important role in carcinogenesis, particularly in BRCA1- and BRCA2-mediated carcinogenesis. A single nucleotide polymorphism (SNP) in the promoter region of MDM2 (309T>G, rs2279744) and a coding SNP of TP53 (Arg72Pro, rs1042522) have been shown to be(More)
  • Al-Essa, Al-Shamsan L, +39 authors Eusebio F
  • 2005
MT. " The relationship of plasma glutamine to ammonium and of glycine to acid-base balance in propionic academia, " Poll-The BT. " Magnetic resonance imaging and spectroscopy of the brain in propionic acidemia: clinical and biochemical considerations, " manifestations of methylmalonic and propionic acidaemia: a description based on 38 cases, " Br J "(More)
Executive Directors 1. Cell-permeable intrinsic cellular inhibitors of apoptosis protect and rescue intestinal epithelial cells from radiation-induced cell death. Research on Cancer Therapy with Carbon Beams 1. Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience. 2. Usefulness of J-CAPRA score for high-risk prostate cancer(More)
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