Marclesson S Alves

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406 Background: Pheochromocytomas/paragangliomas (PC/PG) are rare diseases, but may be responsible for lower quality of life to patients,if progressive or metastatic when malignant. Recently, some benefit has been reported with the use of palliative tyrosine-kinase inhibitors (TKI),such as sunitinib, already approved for kidney cancer. METHODS Review of(More)
466 Background: Sunitinib, a multitarget tyrosine-kinase inhibitor, has become a standard of care for first-line low and intermediate risk metastatic renal cell carcinoma (mRCC). Sunitinib-induced hypothyroidism and hypertension have been correlated with better outcomes in those patients. METHODS Fifty patients with mRCC, treated in the first-line with(More)
Tetracyclines are produced by several pharmaceutical industries, mainly as capsule dosage form. This paper aimed to evaluate quality performance of commercially available tetracycline and oxytetracycline hydrochloride capsules and doxycycline hydrochloride enteric-coated tablets by means of in vitro dissolution test. 36 samples from 12 different producers(More)
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