Marcin Zaradzki

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OBJECTIVES Marfan syndrome is an autosomal dominant inherited disorder of connective tissue. The vascular complications of Marfan syndrome have the biggest impact on life expectancy. The aorta of Marfan patients reveals degradation of elastin layers caused by increased proteolytic activity of matrix metalloproteinases (MMPs). In this study we performed(More)
Aortenerkrankungen sind komplexe und herausfordernde chirurgische Krankheitsbilder, deren molekulare Grundlagen immer noch erforscht werden. Die häufigsten Aortopathien sind Aneurysmen der abdominellen und der thorakalen Aorta. Für beide Krankheitsbilder ist die einzige lebensverlängernde Therapie die chirurgische bzw. endovaskuläre Intervention. Um einen(More)
INTRODUCTION Ischemic colitis (IC) remains a great threat after cardiac surgery with use of extracorporeal circulation. We aimed to identify predictive risk factors and influence of early catecholamine therapy for this disease. METHODS We prospectively collected and analyzed data of 224 patients, who underwent laparotomy due to IC after initial cardiac(More)
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