Marcia C. F. Carvalho

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Chelating therapy has been reported as a useful approach for counteracting mercurial toxicity. Moreover, 2,3-dimercapto-1-propanesulfonic acid (DMPS), a tissue-permeable metal chelator, was found to increase urinary mercury excretion and decrease mercury content in rat brain after methylmercury (MeHg) exposure. We evaluated the capability of DMPS to reduce(More)
Lead intoxication affects the central nervous system and produces structural disorders and behavioral deficits in several animal species. Although lead neurotoxicity is a well-reported phenomenon, studies on the developmental neurotoxicity induced by this metal in avian are scarce. The aim of this study was to evaluate how a single dose of 28 mug lead(More)
Este trabalho propõe uma integração da abordagem CREWS L'ecritoire baseado em cenários com a abordagem de casos de usos descrita por Regnell et al e o Método GBRAM baseado em objetivos. Dessa forma são adicionados ao trabalho de Regnell et al a noção de pedaço de requerimento (RC), as estratégias de descoberta do objetivo através dos relacionamentos
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