Marcelo Vaz Perez

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STUDY OBJECTIVES To define the analgesic efficacy, and to identify a possible site of action, of epidural and intraarticular neostigmine. DESIGN Randomized, double-blind study. SETTING Postoperative analgesia, teaching hospital. PATIENTS 58 ASA physical status I and II patients undergoing knee surgery. INTERVENTIONS All patients were premedicated(More)
BACKGROUND The use of ultrasound (US) in regional anaesthesia enables a reduction in the local anaesthetic volume. The present study aimed to determine the minimum effective volume (MEV(90)) of 0.5% bupivacaine with epinephrine for interscalene brachial plexus block (ISBPB). METHODS The volume of the anaesthetic was determined using a step-up/step-down(More)
STUDY OBJECTIVES To examine analgesia and adverse effects following transdermal application of nitroglycerine (a nitric oxide generator) combined with oral morphine, in cancer pain patients. DESIGN Randomized, double-blind study. SETTING Teaching hospital. PATIENTS 36 patients suffering from cancer pain. INTERVENTIONS Patients were divided into two(More)
BACKGROUND AND OBJECTIVES Low back pain is a common syndrome that causes disability and absence from work. Although there are several causes, the most common type of back pain is nonspecific. Exercises are often used to treat back pain, but there is controversy regarding its effectiveness. The aim of this paper is to review exercises for nonspecific low(More)
BACKGROUND AND OBJECTIVES Malignant hyperthermia (MH) is a pharmacogenetic disease that causes abnormal hypermetabolic reaction to halogenated anesthetics and/or depolarizing muscle relaxants. In Brazil, there is a hotline telephone service for MH since 1991, available 24 hours a day in São Paulo. This article analyzes the activity of the Brazilian hotline(More)
The aim of this study was to determine whether IGF-1 and INS are able to induce HLA-DR antigen expression (AgHLA-DR) in cultured human thyrocytes. Cytotoxicity assay in thyroid epithelial cells (cultured for 7 days to avoid spontaneous antigen expression) from 14 patients operated due to different thyroidal diseases, was used to assess HLA-DR expression.(More)
BACKGROUND AND OBJECTIVES The interscalene is one of the most common approaches used in brachial plexus block. However, the association of this approach with the ipsilateral blockade of the phrenic nerve has been demonstrated. The resulting diaphragmatic dysfunction causes changes in lung mechanics, which can be potentially deleterious in patients with(More)