Marcelo Roberto Pereira Freitas

Learn More
BACKGROUND Glioblastoma (GBM) confers a dismal prognosis despite advances in current therapy. Cancer-testis antigens (CTA) comprise families of tumor-associated antigens that are immunogenic in different cancers. The aim of this study was to determine the expression profile of a large number of CTA genes in GBM. METHODS We selected, from 153 CTA genes,(More)
INTRODUCTION Cerebellar high-grade astrocytoma is uncommon. Although more prone to present cerebrospinal fluid dissemination, the cerebellar location is not particularly related to the occurrence of extra-cranial metastases, which are also unusual in supratentorial malignant gliomas. CASE REPORT A 46 year-old man with cerebellar anaplastic astrocytoma who(More)
e12518 Background: Glioblastoma (GBM) is a highly invasive and aggressive tumor which confers a dismal prognosis despite advances of current therapy. Cancer vaccines have been utilized as treatment of other tumors and might be an option for brain tumors. Cancer-testis (CT) genes represent promising targets for immunotherapeutic approaches as they are(More)
OBJECTIVE To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. METHODS A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. RESULTS Kappa value between Oncotype DX and standard(More)
  • 1