Marcelo Luis Altenhofen da Silva

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A novel series of feruloyl-donepezil hybrid compounds were designed, synthesized and evaluated as multitarget drug candidates for the treatment of Alzheimer's Disease (AD). In vitro results revealed potent acetylcholinesterase (AChE) inhibitory activity for some of these compounds and all of them showed moderate antioxidant properties. Compounds 12a, 12b(More)
The most common indication for primary gluteoplasty is the aesthetic correction of gluteal hypoplasia; secondary gluteoplasty is directed toward asymmetry from misplaced implants, trauma or infection of the implant, and treatment of congenital and acquired deformities. In this study, the authors describe a new suture maneuver designed to improve the result(More)
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