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Antimanic-like effect of tamoxifen is not reproduced by acute or chronic administration of medroxyprogesterone or clomiphene
Tamoxifen, a protein kinase C (PKC) inhibitor and antiestrogenic drug, has clinical antimanic effects and blocks psychostimulant-induced hyperlocomotion. Medroxyprogesterone (MPA), which hasExpand
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Memory Impairment Induced by Sodium Fluoride is Associated with Changes in Brain Monoamine Levels
Previous studies suggest that sodium fluoride (NaF) can impair performance in some memory tasks, such as open-field habituation and two-way active avoidance. In the present study, we evaluated theExpand
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Reduction of ethanol intake by corticotropin-releasing factor receptor-1 antagonist in “heavy-drinking” mice in a free-choice paradigm
RationaleWe hypothesized that the corticotropin-releasing factor (CRF) system is hyperresponsive in animals with high ethanol intake, which exhibits a reduction of ethanol intake when administeredExpand
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A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability
TLDR
We have developed a mass spectrometry imaging method to visualize and quantify the brain distribution of drugs with varying blood‐brain barrier permeability. Expand
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Amphetamine-induced appetitive 50-kHz calls in rats: a marker of affect in mania?
RationaleAnimal models aimed to mimic mania have in common the lack of genuine affective parameters. Although rodent amphetamine-induced hyperlocomotion is a frequently used behavioral model ofExpand
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The antimanic‐like effect of phenytoin and carbamazepine on methylphenidate‐induced hyperlocomotion: role of voltage‐gated sodium channels
The objective of this study was to verify whether phenytoin modifies methylphenidate‐induced hyperlocomotion, an animal model for screening antimanic‐like drugs, and also evaluate the effect ofExpand
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Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine
The trace amine-associated receptor 1 (TAAR1) is expressed by dopaminergic neurons, but the precise influence of trace amines upon their functional activity remains to be fully characterized. Here,Expand
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GRP78 Level Is Altered in the Brain, but Not in Plasma or Cerebrospinal Fluid in Parkinson’s Disease Patients
Accumulation of misfolded proteins results in cellular stress, and is detected by specific sensors in the endoplasmic reticulum, collectively known as the unfolded protein response (UPR). It has beenExpand
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Comparison of MODIS and Landsat-8 retrievals of Chlorophyll-a and water temperature over Lake Titicaca
TLDR
Chlorophyll-a concentration ([Chl-a]) and Lake Surface Temperature (LST) were retrieved in Lake Titicaca (Peru-Bolivia) using MODIS and Landsat-8 images. Expand
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Physicochemical properties of soil and biomass in sugarcane harvesting systems.
The different crop management systems used and the intense traffic of machines have caused physical and chemical changes in soils cultivated with sugarcane. In this study, we aimed to evaluate theExpand
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