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- Xingyong Wu, Hongjian Liu, +6 authors Marcel P Bruchez
- Nature Biotechnology
- 2003
Semiconductor quantum dots (QDs) are among the most promising emerging fluorescent labels for cellular imaging. However, it is unclear whether QDs, which are nanoparticles rather than small… (More)
- Marcel P Bruchez, Mario M. Moronne, Pham Tien Gin, S. Weiß, A Paul Alivisatos
- Science
- 1998
Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable,… (More)
- Byron T. Ballou, B. Christoffer Lagerholm, Lauren Ernst, Marcel P Bruchez, Alan Waggoner
- Bioconjugate chemistry
- 2004
Quantum dots having four different surface coatings were tested for use in in vivo imaging. Localization was successfully monitored by fluorescence imaging of living animals, by necropsy, by frozen… (More)
- Daniel R Larson, Warren R. Zipfel, +4 authors Watt W. Webb
- Science
- 2003
The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton microscopy enables multicolor imaging in demanding biological environments such as living tissue. We… (More)
- A Paul Alivisatos, Kai Johnsson, +4 authors Peter G. Schultz
- Nature
- 1996
Patterning matter on the nanometre scale is an important objective of current materials chemistry and physics. It is driven by both the need to further miniaturize electronic components and the fact… (More)
- Chris Szent-Gyorgyi, Robyn L Stanfield, +6 authors Marcel P Bruchez
- Journal of molecular biology
- 2013
We report that a symmetric small-molecule ligand mediates the assembly of antibody light chain variable domains (VLs) into a correspondent symmetric ternary complex with novel interfaces. The L5*… (More)
- H. M. Jackson, Osman Muhammad, +5 authors Steven A. Toms
- Neurosurgery
- 2007
OBJECTIVE
The identification of neoplastic tissue within normal brain during biopsy and tumor resection remains a problem in the operative management of gliomas. A variety of nanoparticles are… (More)
- Subhasish K. Chakraborty, James A. J. Fitzpatrick, +4 authors Byron T. Ballou
- Nano letters
- 2007
Cholera toxin subunit B (CTB)--quantum dot conjugates were developed for labeling mammalian cells. The conjugates were internalized by all tested cell lines into small vesicles dispersed throughout… (More)
- Byron T. Ballou, Lauren Ernst, +4 authors Marcel P Bruchez
- Bioconjugate chemistry
- 2007
We demonstrate that quantum dots injected into two model tumors rapidly migrate to sentinel lymph nodes. PEG-coated quantum dots having terminal carboxyl, amino, or methoxyl groups all migrated from… (More)
- Christopher Szent-Gyorgyi, Brigitte F Schmidt, +11 authors Alan Waggoner
- Nature Biotechnology
- 2008
Imaging of live cells has been revolutionized by genetically encoded fluorescent probes, most famously green and other fluorescent proteins, but also peptide tags that bind exogenous fluorophores. We… (More)