Marcel Ackermann

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Preparations of isolated brain postsynaptic densities (PSDs) contain a characteristic set of proteins among which the most prominent has a molecular weight of 50,000. Following the suggestion that this major PSD protein might be related to a similarly sized component of neurofilaments (F. Blomberg et al ., 1977, J. Cell Biol ., 74 :214-225), we searched for(More)
Hydrogen sulfide (H₂S) can be consumed by both invertebrates and vertebrates as an inorganic substrate. The pathway metabolizing H₂S probably involves three mitochondrial enzymes, one of which is sulfide-quinone oxidoreductase (SQR), known as sulfide-quinone reductase-like protein (SQRDL) in vertebrates. Evidence from fission yeast suggests that SQR might(More)
zfNLRR is a novel transmembrane protein that is most prominently expressed during regeneration of the zebrafish central nervous system. Retinal ganglion cells and descending spinal cord neurons strongly increase zfNLRR mRNA levels after axotomy in the adult. In contrast, during development expression is hardly detectable and is restricted to a few sensory(More)
Hydrogen sulfide (H2S) is the first inorganic compound identified as both a substrate for mitochondrial oxidative phosphorylation and a transmitter in mammalian cells. H2S seems to mediate effects that are correlated with those of nitric oxide (NO) by a reciprocal regulation. Moreover, H2S is consumed by mitochondrial oxidation mediated by sulfide-quinone(More)
In this work, a novel approach for the initialization of switching linear dynamic models (SLDMs) as dynamic models for the trajectory of speech features is proposed. Borrowing ideas from the " k-means++ "-algorithm, the goal of this approach is to find distinctly different SLDMs, modelling the complex dynamics of the speech features, already at the(More)
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