Learn More
The X-linked dominant trait focal dermal hypoplasia (FDH, Goltz syndrome) is a developmental defect with focal distribution of affected tissues due to a block of Wnt signal transmission from cells carrying a detrimental PORCN mutation on an active X-chromosome. Molecular characterization of 24 unrelated patients from different ethnic backgrounds revealed 23(More)
The complexity of modern vehicular embedded systems is constantly rising. In addition, distributed embedded systems like automobiles often implement safety-relevant applications which have a high demands on safety and reliability. This poses a great challenge for the design of these systems. Self-adaptation may overcome these challenges and enhance the(More)
In this work, we consider runtime adaptation in networked embedded systems with tight real-time constraints. For such systems, we aim to adapt the placement of software components on networked hardware components at runtime without violating real-time constraints. We develop constraints for such an adaptation process and show the applicability to networked(More)
Modern distributed embedded systems are reaching an extreme complexity which is very hard to master with traditional methods. Particularly the need for these systems to adapt their behavior autonomously at runtime to changing conditions is a demanding challenge. Since most industrial application domains of distributed embedded systems have high demands on(More)
Architecture description languages (ADLs) allow specifying system information in architecture models. These are generally used for capturing early design decisions concerning system or software development. Therefore, ADLs can be utilized for an early and iterative validation of the modelled system. With EAST-ADL an automotive-specific ADL is defined which(More)