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  • Harvey I. Skulnick, James H. Ludens, +4 authors Wendell Wierenga
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1986 (First Publication: 1 August 1986)
  • In an extensive analysis of the antiviral and interferon-induction structure-activity relationship of 6-arylpyrimidinones we found that modifications at positions 1-4 of the pyrimidine ring resultedContinue Reading
  • A. Robert, Paul A. Aristoff, Marc Wendling, Frances Kimball, Walter L. Miller, Robert R. Gorman
  • Medicine
  • Prostaglandins
  • 1985 (First Publication: 1 October 1985)
  • U-68,215 [15-Cyclohexyl-9-deoxo-13,14-dihydro-2',9 alpha-methano-4,5,6,16,17,18,19,20-octanor-3-oxa-3,7-(1', 3'-interphenylene)-PGE1] is a stable prostacyclin analog. When given orally to rats, it isContinue Reading