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This study reports a combined scalp current density (SCD) and dipole model analysis of the N1 wave of the auditory event-related potentials evoked by 1 kHz tone bursts delivered every second. The SCD distributions revealed: (i) a sink and a source of current reversing in polarity at the inferotemporal level of each hemiscalp, compatible with neural(More)
This paper presents a study of the intrinsic localization error bias due to the use of a spherical geometry model on EEG simulated data obtained from realistically shaped models. About 2000 dipoles were randomly chosen on the segmented cortex surface of a particular subject. Forward calculations were performed using a uniformly meshed model for each dipole(More)
Scalp current density analysis of the auditory evoked response to 1-kHz tone bursts delivered at various interstimulus intervals (ISIs) (from 1 s to 2 min in separate runs) shows that two different frontal components can be observed and functionally dissociated in the N1 time range: one is elicited for all ISIs, peaks at about 95 ms poststimulus, and has a(More)
In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus. After conditioning, the conditioned stimulus elicits a fear response characterized by a wide range of behavioral and physiological responses. Despite the(More)
Although the amygdala seems to be essential to the formation and storage of fear memories, it might store only some aspects of the aversive event and facilitate the storage of more specific sensory aspects in cortical areas. We addressed the time course of amygdala and cortical activation in the context of odor fear conditioning in rats. Using high temporal(More)
Human olfactory perception can be measured using psychophysical tools or more complex odor generating devices systems, namely olfactometers. The present paper is aimed at presenting a new inexpensive, non-voluminous portable olfactometer adapted for human fMRI experiments. The system adjusts odorant stimulus presentation to human nasal respiration and(More)
BACKGROUND The impact of respiratory dynamics on odor response has been poorly studied at the olfactory bulb level. However, it has been shown that sniffing in the behaving rodent is highly dynamic and varies both in frequency and flow rate. Bulbar odor response could vary with these sniffing parameter variations. Consequently, it is necessary to understand(More)
Odor-evoked activity in the olfactory bulb displays both spatial and temporal organization. The difficulty when assessing spatio-temporal dynamics of olfactory representation is to find a method that reconciles the appropriate resolution for both dimensions. Imaging methods based on optical recordings can reach high temporal and spatial resolution but are(More)
BACKGROUND Odor hedonic perception relies on decoding the physicochemical properties of odorant molecules and can be influenced in humans by semantic knowledge. The effect of semantic knowledge on such prewired hedonic processing over the life span has remained unclear. METHODOLOGY/PRINCIPAL FINDINGS The present study measured hedonic response to odors in(More)
One important aspect of odor hedonics is its plasticity during human development. The present study set out to probe the modulators of such olfactory change during that period by testing the hypothesis that language and semantic representations of objects are strong organizers of odor liking. To this end, 15 three-year-old children were tested in a(More)