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In the absence of disease, microvessels provide vessel wall nutrients to the tunica media, while the intima is fed by oxygen diffusion from the lumen. As disease evolves and the tunica intima thickens, oxygen diffusion is impaired, and microvessels become the major source for nutrients to the vessel wall. Microvessels serve as a port of entry for(More)
BACKGROUND Previous overviews suggested that hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins), but not other lipid-lowering therapy (LLT), may reduce stroke incidence in coronary patients. OBJECTIVE To investigate the amplitude and sources of heterogeneity of LLT effects on stroke prevention. METHODS We searched the literature from 1966(More)
BACKGROUND Arterial thrombosis plays a critical role in acute coronary syndromes and stroke. Therefore, the ability to detect thrombus in vivo has a significant clinical implication. Magnetic resonance imaging (MRI) has shown promise in noninvasive thrombus detection. However, thrombus characterization and age definition remain difficult. We sought to(More)
A 44-year-old woman was referred to our cardiology department because of septicemia caused by Listeria monocytogenes and sick sinus syndrome. The patient had a history of paresthesia of the limbs 7 years earlier with multiple sclerosis–like lesions on brain magnetic resonance imaging and positive tests for antinuclear antibodies and anti-double-stranded DNA(More)
Our objective was to determine the diagnostic accuracy of a free-breathing diffusion-weighted single-shot echo-planar magnetic resonance imaging (FBDW-SSEPI) technique with parallel imaging and high diffusion factor value (b = 1000 s/mm2) in the detection of primary rectal adenocarcinomas. Thirty-one patients (14M and 17F; mean age 67 years) with(More)
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