Marc Scherer

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Hyperglycaemia and insulin resistance have been linked to diastolic dysfunction experimentally. We investigated the association between glucose metabolism and diastolic function along the whole spectrum of glucose metabolism states. In the observational Diagnostic Trial on Prevalence and Clinical Course of Diastolic Dysfunction and Diastolic Heart Failure(More)
BACKGROUND Coronary endothelial dysfunction may be an early marker for cardiac allograft vasculopathy (CAV) in orthotopic heart transplant recipients. Using serial studies with intravascular ultrasound and Doppler flow-wire measurements, we have previously demonstrated that annual decrements in coronary endothelial function are associated with progressive(More)
In this double-blind, randomised, placebo-controlled cross-over study the respiratory effects of Mr 2264 Cl2 × 5 mg IV, a new partial opiate receptor agonist, were investigated and compared with the respiratory effects of morphine 2 × 10 mg IV and placebo. As primary end-points, the slope of the rebreathing curve (dV'/dPCO2ET) and V55 (ventilation at(More)
This paper focuses on designing a framework for the activation of tertiary control reserves in order to improve frequency control performance. Considering the fact that tertiary control reserves are not immediately available and, therefore, must be requested in advance, a pattern is proposed based on a Model Predictive Control (MPC) scheme. Linear(More)
This paper presents the methodology and results of a risk assessment to match the frequency containment dimensioning and resulting security performance by analyzing the relationship between the available amount of frequency-response reserves and the frequency quality performance in the European power system. The proposed dimensioning technique is simulated(More)
The successful operation of interconnected power systems requires the balance of electricity generation and consumption. This is performed by frequency control that comprises three level control processes known as primary, secondary, and tertiary control. First, primary control stabilizes frequency within some seconds. Next, secondary control keeps the(More)