Marc S. Schwartz

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OBJECTIVES/HYPOTHESIS Compare vestibular schwannoma (VS) surgical outcome between patients with prior irradiation and those not previously treated. STUDY DESIGN Retrospective review with matched control group. METHODS Review of tumor adherence to the facial nerve, facial nerve grade, and complications in 38 patients with radiotherapy as a primary(More)
OBJECTIVE To assess the duration of hearing preservation from time of vestibular schwannoma middle fossa decompression with short-term and 1-year hearing preservation rates. STUDY DESIGN Retrospective case review. SETTING Tertiary referral center. PATIENTS Patients with and without neurofibromatosis type 2 who underwent middle fossa decompression. We(More)
The development of cochlear implantation has allowed the majority of patients deafened after the development of language to regain significant auditory benefit. In a subset of patients, however, loss of hearing results from destruction of the cochlear nerves, rendering cochlear implantation ineffective. The most common cause of bilateral destruction of the(More)
OBJECTIVE To determine whether partial tumor removal in large vestibular schwannoma improves facial nerve outcomes while maintaining a low risk of tumor regrowth/recurrence. STUDY DESIGN Retrospective chart review and prospective database. SETTING Tertiary neurotologic referral center. PATIENTS Four hundred patients with a vestibular schwannoma of 2.5(More)
OBJECT Spontaneous intracranial hypotension is an important cause of headaches and an underlying spinal CSF leak can be demonstrated in most patients. Whether CSF leaks at the level of the skull base can cause spontaneous intracranial hypotension remains a matter of controversy. The authors' aim was to examine the frequency of skull base CSF leaks as the(More)
OBJECTIVE Determine whether more conservative management for surgical salvage after failed radiation leads to better facial nerve outcomes. STUDY DESIGN "Retrospective" review using prospectively planned database. SETTING Private practice, tertiary neurotology/neurosurgery referral center. PATIENTS A series of 73 patients with vestibular schwannoma,(More)
OBJECTIVE To design a treatment algorithm based on experience with facial nerve schwannomas (FNS) over a 30-year period. STUDY DESIGN Retrospective chart review. METHOD Seventy-nine patients with facial nerve schwannomas seen from 1979 through 2009 at a tertiary referral private otologic practice were categorized by treatment modality. Interventions(More)
This study relates the performance of college students in introductory science courses to the amount of content covered in their high school science courses. The sample includes 8310 students in introductory biology, chemistry, or physics courses in 55 randomly chosen U.S. colleges and universities. Students who reported covering at least 1 major topic in(More)
BACKGROUND Developing methods for protecting organisms in metal-polluted environments is contingent upon our understanding of cellular detoxification mechanisms. In this regard, half-molecule ATP-binding cassette (ABC) transporters of the HMT-1 subfamily are required for cadmium (Cd) detoxification. HMTs have conserved structural architecture that(More)