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— Patients that undergo treatment in the epilepsy clinic Kempenhaeghe in the Netherlands are being monitored with different sensory signals, including audio. In this paper a new patient monitoring system for the detection of epileptic seizures through audio classification is proposed. The proposed system enables automated detection of epileptic seizures,(More)
— Early diagnosis of Parkinson's disease (PD) is of immense importance, since clinical symptoms do not occur until substantial parts of the brain stem have been irreparably damaged. Recent work suggests that by means of transcranial sonog-raphy (TCS) it is possible to determine the formation of mono-genic forms of parkinsonism at a very early state. In TCS(More)
BACKGROUND Scarring of the liver is the result of prolonged exposure to exogenous or endogenous stimuli. At the onset of fibrosis, quiescent hepatic stellate cells (HSCs) activate and transdifferentiate into matrix producing, myofibroblast-like cells. AIM AND METHODS To identify key players during early HSC activation, gene expression profiling was(More)
This research explores to what extent Information and Communication Technology (ICT)-based information management methods can help to improve efficiency and effectiveness of health services in sub-Saharan hospitals and how clinical information can be made available for secondary use enabling non-redundant reporting of health- and care performance(More)
— Accurate image registration is a necessary prerequisite for many diagnostic and therapy planning procedures where complementary information from different images has to be combined. The design of robust and reliable non-parametric registration schemes is currently a very active research area. Modern approaches combine the pure registration scheme with(More)
Collaborative ontology-engineering methods usually prescribe a set of processes, activities, stakeholders, and the roles each stakeholder plays in these activities. We, however, believe that (a) the stakeholder community of each ontology-engineering project is different, and (b) one can observe different types of user behavior. It may thus very well be that(More)
In this retrospective study, the authors monitored the patient health coverage in 6 Rwandan hospitals in the period between 2011 and 2014. Among the 6 hospitals, 2 are third level hospitals, 2 district hospitals and 2 private hospitals. Patient insurance and financial data were extracted and analyzed from OpenClinic GA, an open source hospital information(More)
Since 2011, the Regional e-Health Center of Excellence in Rwanda (REHCE) has run an MSc in Health Informatics programme (MSc HI). A programme review was commissioned in February 2014 after 2 cohorts of students completed the post-graduate certificate and diploma courses and most students had started preparatory activity for their master dissertation. The(More)
From 2007 through 2014, the authors participated in the implementation of open source hospital information systems (HIS) in 19 hospitals in Rwanda, Burundi, DR Congo, Congo-Brazzaville, Gabon, and Mali. Most of these implementations were successful, but some failed. At the end of a seven-year implementation effort, a number of risk factors, facilitators,(More)