Marc N. Coel

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UNLABELLED This study compared 18F-fluorocholine uptake in malignant and benign areas of the prostate at 2 time points to determine the suitability of delayed or dual-phase 18F-fluorocholine PET for localizing malignancy in the prostate gland. METHODS Twenty-six men (15 newly diagnosed with prostate cancer, 2 with recurrent prostate cancer, 6 with no(More)
PURPOSE We evaluated positron emission tomography (PET) with fluorine fluorocholine (F FCH) for the pretreatment localization of prostate cancer. MATERIALS AND METHODS A total of 17 patients with prostate cancer who had not yet received treatment for the disease underwent whole body PET following intravenous administration of 3.3 to 4 MBq/kg F FCH. PET(More)
UNLABELLED The current perception of using contrast-enhanced CT (CECT) for attenuation correction (AC) is that of caution, as it might lead to erroneously elevated (18)F-FDG uptake on the PET scan. This study evaluates in vivo whether an intravenous iodinated contrast agent produces a significant AC artifact in the level of standardized uptake value (SUV)(More)
PURPOSE To prospectively determine whether differences between benign and malignant brain lesions can be depicted with fluorine 18 ((18)F) fluorocholine positron emission tomography (PET). MATERIALS AND METHODS Thirty consecutive patients (14 women, 16 men; age range, 26-79 years) with solitary brain lesions that were enhanced at magnetic resonance (MR)(More)
The aim of this study was to compare the performance of three different software packages for the calculation of ejection fraction (EF) and end diastolic volume (EDV) from gated myocardial single photon emission computed tomography studies. Two hundred patients undergoing gated stress myocardial perfusion scans were analysed retrospectively. Patients were(More)
The choline transporter and choline kinase enzyme frequently are overexpressed in malignancy. Therefore, positron-emitter-labeled compounds derived from choline have the potential to serve as oncologic probes for positron emission tomography. The fluorine-18 ((18)F)-labeled choline derivative fluorocholine (FCH) in particular has demonstrated potential(More)
OBJECTIVE The purpose of this study was to determine what changes might be detected on MR images of patients with chronic lateral epicondylitis (tennis elbow) that could explain why some cases are resistant to therapy. SUBJECTS AND METHODS Seven consecutive patients with chronic lateral epicondylitis were included. The diagnosis was based on symptoms and(More)
For fifty-five patients with acute low-back pain or radicular pain, ascending lumbar venography was as accurate as myelography (86 per cent) in localized herniation of a lumbar disc in surgically proved cases. Myelography and lumbar venography are complementary diagnostic studies which should be used together in doubtful cases. Lumbar venography is easily(More)
BACKGROUND Choline metabolism is often abnormal in malignant brain tumors. METHODS Brain positron emission tomography (PET) imaging with F-18 fluorocholine (FCH) was performed on 2 patients with intracranial lesions suspected to be high-grade malignant gliomas on the basis of magnetic resonance (MR) imaging and multivoxel 1H-MR spectroscopic imaging(More)
UNLABELLED This study investigated the prognostic significance of metabolically active tumor volume (MATV) measurements applied to (18)F-fluorocholine PET/CT in castration-resistant prostate cancer (CRPC). METHODS (18)F-fluorocholine PET/CT imaging was performed on 30 patients with CRPC. Metastatic disease was quantified on the basis of maximum(More)