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We develop a statistical approach for characterizing uncertainty in predictions that are made with the aid of a computer simulation model. Typically, the computer simulation code models a physical system and requires a set of inputs – some known and specified, others unknown. A limited amount of field data from the true physical system are available to(More)
PURPOSE Little is known about the ocular oxygen consumption rate (QO2) in human diseases. Alterations in QO2 must occur in many conditions, such as retinal ischemia. We present a method of estimating QO2 that eventually could be used in patients during vitrectomy surgery. METHODS We performed vitreoperfusion (i.e., perfusion of the vitreous cavity after(More)