Marc J. Spirn

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BACKGROUND Since they were first derived more than three decades ago, embryonic stem cells have been proposed as a source of replacement cells in regenerative medicine, but their plasticity and unlimited capacity for self-renewal raises concerns about their safety, including tumour formation ability, potential immune rejection, and the risk of(More)
BACKGROUND Intravitreal injection of triamcinolone has been advocated to treat exudative macular diseases such as macular edema and choroidal neovascularization. OBJECTIVE To describe 7 patients who developed a clinical picture simulating endophthalmitis after intravitreal triamcinolone injection. METHODS Intravitreal triamcinolone injections were(More)
One's being able to allocate attention to particular regions or properties of the visual field is fundamental to visual information processing. Visual attention determines what input is carefully analyzed and what input is more or less ignored. But at what stage of the visual system is this process evident? We describe three experiments that demonstrate an(More)
PURPOSE OF REVIEW The history and development of 25-gauge and 23-gauge vitrectomy are reviewed in this paper and compared with 20-gauge vitrectomy, the historical gold standard. Current advantages and disadvantages of each are delineated. RECENT FINDINGS Transconjunctival sutureless vitrectomy continues to offer advantages of increased patient comfort(More)
PURPOSE To evaluate same-day combination intravitreal bevacizumab/panretinal photocoagulation (PRP) for the treatment of neovascular glaucoma (NVG) compared with PRP alone. METHODS This was an institutional review board-approved, retrospective, consecutive case-control study of patients receiving same-day combination bevacizumab/PRP or PRP alone as(More)
AIMS To review the epidemiology, diagnosis and changing treatment paradigm of ocular candidiasis, and report current prevalence rates and risk factors at one inpatient hospital. DESIGN Retrospective review; systematic literature review. METHODS All Wills Eye Institute inpatient ophthalmology consultations from Thomas Jefferson University Hospital were(More)
PURPOSE To report the frequency of postoperative vitreous hemorrhage (VH) in eyes that underwent primary 23-gauge pars plana vitrectomy (PPV) for nonclearing VH resulting from proliferative diabetic retinopathy, as well as associated risk factors. DESIGN Retrospective, consecutive, interventional case series. METHODS SETTING Institutional (Retina(More)