• Publications
  • Influence
Inflammatory bowel disease: clinical aspects and treatments
Inflammatory bowel disease (IBD) is defined as a chronic intestinal inflammation that results from host-microbial interactions in a genetically susceptible individual. IBDs are a group of autoimmuneExpand
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Autistic spectrum disorders: A review of clinical features, theories and diagnosis
  • Marc Fakhoury
  • Medicine, Psychology
  • International Journal of Developmental…
  • 1 June 2015
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders that is among the most severe in terms of prevalence, morbidity and impact to the society. It is characterized by complexExpand
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Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy
  • Marc Fakhoury
  • Psychology, Medicine
  • Current neuropharmacology
  • 19 July 2017
Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by the progressive loss of neurons, which typically leads to severe impairments in cognitive functionsExpand
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Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders
  • Marc Fakhoury
  • Psychology, Medicine
  • Molecular Neurobiology
  • 1 July 2016
Major depressive disorder (MDD) is a heritable neuropsychiatric disease associated with severe changes at cellular and molecular levels. Its diagnosis mainly relies on the characterization of a wideExpand
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Role of Immunity and Inflammation in the Pathophysiology of Neurodegenerative Diseases
Neurodegenerative diseases are the result of progressive loss of neurons and axons in the central nervous system (CNS), which can lead to cognition and motor dysfunction. It is well known that CNSExpand
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The habenula in psychiatric disorders: More than three decades of translational investigation
  • Marc Fakhoury
  • Psychology, Medicine
  • Neuroscience & Biobehavioral Reviews
  • 13 February 2017
HighlightsThe habenula is an epithalamic structure linking forebrain to midbrain regions.DBS of the habenula is associated with an amelioration of depressive‐live symptoms.Schizophrenia isExpand
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New insights into the neurobiological mechanisms of major depressive disorders.
  • Marc Fakhoury
  • Psychology, Medicine
  • General hospital psychiatry
  • 1 March 2015
OBJECTIVE To review the current evidence about the neurobiological mechanisms in major depressive disorders (MDD) and the key findings from studies using neuroimaging tools and animal models. Expand
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Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study
Gliclazide (G) is an antidiabetic drug commonly used in type 2 diabetes. It has extrapancreatic hypoglycemic effects, which makes it a good candidate in type 1 diabetes (T1D). In previous studies, weExpand
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Spinal cord injury: overview of experimental approaches used to restore locomotor activity
Abstract Spinal cord injury affects more than 2.5 million people worldwide and can lead to paraplegia and quadriplegia. Anatomical discontinuity in the spinal cord results in disruption of theExpand
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Immune-mediated processes in neurodegeneration: where do we stand?
  • Marc Fakhoury
  • Biology, Medicine
  • Journal of Neurology
  • 12 February 2016
Neurodegeneration is a pathological condition that predominantly affects neurons. It represents a large spectrum of disorders with heterogeneous symptoms and distinct clinical features. In additionExpand
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