Marc Callens

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The antitumoral activity of vorozole, a potent and specific nonsteroidal aromatase inhibitor, against 7,12-dimethylbenz(a)anthracene-induced estrogen-dependent mammary adenocarcinoma was evaluated in 257 Sprague-Dawley rats. Twice daily p.o. administration of 1 and 5 mg/kg of the racemate R 76713 for 42 days induced almost complete regression of tumors,(More)
A strategy for reverse transcriptase polymerase chain reaction (RT-PCR) using multiple primers was developed to detect and to differentiate the seven serotypes of foot-and-mouth disease virus (FMDV) simultaneously, quickly and accurately. The development of the test was carried out on virus isolates grown in tissue culture prior to cDNA synthesis and PCR(More)
In cats, 131 area 18 units with receptive fields 10-50 degrees from the visual axis, were recorded and tested with moving stimuli. These stimuli included light slits, dark bars, single edges, gratings and a random square pattern. 94% of the units were responsive to visual motion. 106 neurones could be classified by a screening procedure based on responses(More)
In paralyzed cats units were recorded from the peripheral projections on area 18. Of 46 cells, 71 percent responded to moving visual stimuli. From this sample 91 percent responded to velocities ranging from 5 to 400 degrees-sec(-1). Within this group, two classes of neurons could be distinguished. The first class had small receptive fields and responded(More)
A highly sensitive detection of swine vesicular disease virus (SVDV) based on a single tube RT-PCR system and digoxigenin (DIG)-PCR-ELISA detection was developed. Using a one tube RT-PCR system, optimisation of the PCR conditions and optimisation of the microwell hybridisation and colourimetric detection of the amplicons resulted in a method that could(More)
In cats, 107 area 18 neurones with identified FR type, 10-50 degrees from the visual axis, were tested for the influence of direction, velocity and amplitude of movement. These three parameters are believed to be the primary parameters of a movement analysing system. 94% of the neurones were influenced by the direction of movement, all of them by the(More)
Two non-vaccinated sheep were experimentally infected with FMDV and one day later 4 other sheep were brought in contact. Although the contact sheep showed no clinical signs, serology indicated that all sheep became infected. Various secretion samples, taken over a period of at least one month, and various tissue samples were examined for the presence of(More)