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- Publications
- Influence
Development and evaluation of cationic amphiphilic antimicrobial 2,5‐diketopiperazines
- Christophe Labrière, N. Kondori, +5 authors J. Svenson
- Chemistry, Medicine
- Journal of peptide science : an official…
- 1 July 2018
Both pathogenic bacteria and fungi are developing resistance to common antimicrobial treatment at an alarming rate. To counteract this development, it is of essence to develop new classes of… Expand
Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor† †Electronic supplementary information (ESI) available: Detailed experimental procedures and…
- Richard Fjellaksel, Marc Boomgaren, R. Sundset, I. Haraldsen, Jørn H Hansen, P. Riss
- Chemistry, Medicine
- MedChemComm
- 14 September 2017
In this communication, we report the synthesis and characterization of a library of small molecule antagonists of the human gonadotropin releasing hormone receptor based upon the… Expand
Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases.
- Zeeshan Muhammad, Susann Skagseth, +6 authors Hanna-Kirsti S. Leiros
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 18 June 2020
Metallo-β-lactamases (MBLs) are an emerging cause of bacterial antibiotic resistance by hydrolysing all classes of β-lactams except monobactams, and the MBLs are not inhibited by clinically available… Expand