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The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2
- A. Schmidt, M. Bickle, T. Beck, M. Hall
- Biology, Medicine
- Cell
- 21 February 1997
The Saccharomyces cerevisiae phosphatidylinositol kinase homolog TOR2 is required for organization of the actin cytoskeleton. Overexpression of RHO1 or RHO2, encoding Rho-like GTPases, or ROM2,… Expand
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2
- M. Bickle, P. Delley, A. Schmidt, M. Hall
- Medicine, Biology
- The EMBO journal
- 15 April 1998
The essential phosphatidylinositol kinase homologue TOR2 of Saccharomyces cerevisiae controls the actin cytoskeleton by activating a GTPase switch consisting of RHO1 (GTPase), ROM2 (GEF) and SAC7… Expand