Marc Alexander Radtke

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BACKGROUND Plaque-type psoriasis produces significant morbidity, has negative effects on patients' health-related quality of life (HRQoL), and represents an economic burden. OBJECTIVES The assessment of disease severity, HRQoL and health care in plaque-type psoriasis in everyday German medical practice. METHODS Details of patients with plaque-type(More)
BACKGROUND Medication adherence and compliance are essential for disease management and can significantly improve outcomes and quality of patient care. The literature suggests that up to 40% of patients do not use their medication as intended. OBJECTIVE To elucidate current knowledge on adherence/compliance in psoriasis. In particular, methods of(More)
BACKGROUND Psoriasis is a common disease affecting all age groups. In contrast to adult psoriasis, only few studies on the epidemiology of childhood psoriasis have been published. OBJECTIVES Assessment of prevalence and comorbidities of juvenile psoriasis in Germany based on health insurance data. METHODS Data were collected from a database of about 1.3(More)
BACKGROUND The introduction of biological agents has considerably changed the treatment of moderate to severe psoriasis. So far only limited data on their cost-effectiveness exist. OBJECTIVE Determination of the cost-effectiveness of biologicals from a German third payer's perspective, assessed over a 12-week period. METHODS Efficacies of the(More)
BACKGROUND Many different forms of treatment are available for psoriasis. The German standard is the national AWMF S3 guideline. A national survey on psoriasis care in 2005 indicated deficits in psoriasis care in Germany. AIM Assessment of the health care situation of patients with psoriasis in Germany. METHODS Nation-wide cross-sectional study, in 142(More)
BACKGROUND Psoriatic arthritis (PsA) is a chronic, systemic, inflammatory disorder characterized by the association of arthritis with psoriasis. Patients with PsA may have a heterogeneous and variable clinical course. Evidence that affected patients can have significant radiographic joint damage, functional impairment, reduced quality of life and long-term(More)
BACKGROUND Although hyperhidrosis is a common and burdensome condition, little is known about the population-based prevalence. OBJECTIVE To evaluate the epidemiology, disease burden and medical care of hyperhidrosis in German adults. METHODS Employees of fifty-two companies underwent skin screenings and interviews including hyperhidrosis questions. (More)
Evaluation of therapeutic benefits from the patient’s perspective is important in medical decision-making and reimbursement. This study aimed at developing and validating an instrument on patient-defined needs and benefits in dermatology. The questionnaire was developed according to international guidelines. The benefit assessment consists of two steps:(More)
Epidemiological studies indicate an increased risk of co-morbidities and an association with other inflammatory diseases in psoriasis. However, most analyses have been performed on small samples of patients. The aim of this study was to evaluate the prevalence of co-morbidities in psoriasis based on a large set of health insurance data. The database of 1.3(More)
BACKGROUND The literature on predictors of health-related quality of life in psoriasis is inconsistent. OBJECTIVE To assess potential predictors of quality of life in psoriasis. METHODS In a cross-sectional study involving 130 dermatological practices and outpatient clinics, data of 1,210 patients with psoriasis were collected. Quality of life was(More)