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BACKGROUND Inconsistent data exist about the efficacy of probiotics in the treatment of constipation. Several studies in adults with constipation showed positive effects of probiotics on constipation. Inconsistent data exist regarding the effect of a single probiotic strain in constipated children. The aim of this pilot study was to determine the effect of(More)
  • Paul E Hyman, Peter J Milla, Marc A Benninga, Geoff P Davidson, David F Fleisher, Jan Taminiau
Recognizing the importance of childhood functional gas-trointestinal disorders in understanding adult functional gastrointestinal disorders, and encouraging clinical and research interest, the Rome Coordinating Committee added a pediatric working team to Rome II in 1999. For Rome III, there was an increase from 1 to 2 pediatric working teams. This report(More)
OBJECTIVES To investigate whether children with functional abdominal pain (FAP) show an attentional bias for their bodily activity, and whether receiving information about bodily activity influenced perception of bodily sensations. METHODS A total of 30 children with FAP and 30 healthy children performed a dot-probe task, in which they were shown sham(More)
AIM Our aim was to study the prevalence and characteristics of constipation in children with profound multiple disabilities, as data in this area are scarce. METHOD A cross-sectional observational study was performed in specialized day-care centres and schools in the Netherlands. The study included 152 children (81 males, 71 females; mean age 9 y 6 mo, SD(More)
BACKGROUND Children with functional constipation report impaired Health-related Quality of Life (HRQoL) in relation to physical complaints and long duration of symptoms. In about one third of children with constipation, symptoms continue into adulthood. Knowledge on HRQoL in adults with constipation persisting from childhood is lacking. OBJECTIVES To(More)
BACKGROUND Nutrilon Omneo (new formula; NF) contains high concentration of sn-2 palmitic acid, a mixture of prebiotic oligosaccharides and partially hydrolyzed whey protein. It is hypothesized that NF positively affects stool characteristics in constipated infants. METHODS Thirty-eight constipated infants, aged 3-20 weeks, were included and randomized to(More)
BACKGROUND Constipation is a frustrating symptom affecting 3% of children worldwide. Randomised controlled trials show that both polyethylene glycol and lactulose are effective in increasing defecation frequency in children with constipation. However, in 30-50%, these children reported abdominal pain, bloating, flatulence, diarrhoea, nausea and bad taste of(More)
OBJECTIVE It has been suggested that the addition of behavioral interventions to laxative therapy improves continence in children with functional fecal incontinence associated with constipation. Our aim was to evaluate the clinical effectiveness of behavioral therapy with laxatives compared with conventional treatment in treating functional constipation in(More)
OBJECTIVE We aimed to review the literature regarding epidemiology of functional abdominal pain disorders in children and to assess its geographic, gender and age distribution including associated risk factors of developing functional abdominal pain. METHODS The Cochrane Library, MEDLINE, EMBASE, CINAHL and PsychInfo databases were systematically searched(More)
OBJECTIVES The aim of the study was to review published evidence and the opinion of practising clinicians on the prevalence and long-term health consequences of functional gastrointestinal symptoms in infants younger than 12 months. METHODS PubMed was searched from inception to November 2014 to find articles reporting the prevalence and long-term health(More)