Marcílio Fontes

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Recently, using an animal model of Charcot-Marie-Tooth human disorder, we showed that ascorbic acid (AA) represses PMP22 gene expression by acting on intracellular cAMP concentrations. In this work, we present kinetics data on the inhibitory effect of AA upon adenylate cyclase activity. The data show that this molecule acts as a competitive inhibitor of the(More)
Poultry colibacillosis due to Avian Pathogenic Escherichia coli (APEC) is responsible for several extra-intestinal pathological conditions, leading to serious economic damage in poultry production. The most commonly associated pathologies are airsacculitis, colisepticemia, and cellulitis in broiler chickens, and salpingitis and peritonitis in broiler(More)
The present study reports eight additional mutations in the connexin32 gene associated with the X-linked form of Charcot-Marie-Tooth disease. One of these mutations was found twice in two apparently unrelated families. This form of the disease is demyelinating and dominant. However, patient selection for mutational screening should not be limited to these(More)
One of the most important biochemical aspects of regeneration, in the early stages, after amputation, is the increase in acid hydrolase activities. During regeneration, 24h after amputation of the anterior part of the body of the polychaeteOwenia fusiformis, we have observed the following events: 1. The increase of3H-Uridine incorporation in microsomal and(More)
Universidade Federal de Campina Grande, Centro de Saúde e Tecnologia Rural, Programa de PósGraduação em Zootecnia, Patos, Paraíba, Brasil. Universidade Federal de Campina Grande, Centro de Saúde e Tecnologia Rural, Unidade Acadêmica de Medicina Veterinária, Patos, Paraíba, Brasil. Empresa Estadual de Pesquisa Agropecuária da Paraíba, João Pessoa, Paraíba,(More)
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