Mara Mignone

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A topographic CEEG investigation was carried out in 20 drug-free, DSM-IIIR diagnosed schizophrenics and in a group of matched healthy controls. The effects of acute and chronic haloperidol treatment were then assessed in the patient group. On the baseline recording, schizophrenics showed a widespread increase in delta, theta 1 and beta 3 amplitude. Acute(More)
Several neuropsychological models of schizophrenia have regarded the syndrome as a disorder of the left hemisphere. However, discrepant experimental findings have been reported. It has been proposed that the different psychopathological dimensions of the syndrome are associated with distinct patterns of hemispheric imbalance. The present study was aimed at(More)
Clozapine is the prototype of a new class of drugs, referred to as 'atypical antipsychotics'. As a matter of fact, the antipsychotic activity of the drug was not predicted by the first studies with quantitative electroencephalography (QEEG), which actually reported an antidepressant pattern. All previous QEEG studies carried out in healthy subjects used a(More)
Quantitative electroencephalogram (QEEG) changes induced by the acute administration of moclobemide (200 mg) in patients with major depression include a transient increase in theta-activity, a slight augmentation of alpha-activity and a sustained increase in beta-activity. This QEEG profile distinguishes moclobemide from sedative antidepressants. A 42-day(More)
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