Mara Lombardi

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Infantile acute hemorrhagic edema (AHE) is a benign condition characterized by a dramatic onset of inflammatory edema and ecchymotic purpura in a target or cockade pattern. It is considered an uncommon form of cutaneous vasculitis occurring in children younger than 2 years of age. The outbreak is frequently preceded by an immunization or various infections.(More)
Melanoma progression is favoured by prevalence, within the micro-environment of primary cutaneous melanoma, of suppressive forces, e.g. exerted by CD4(+) CD25(+) FOXP3(+) regulatory T lymphocytes, over anti-melanoma immunity, e.g. exerted by CD8(+) cytolytic T lymphocytes. The CD27 glycoprotein is crucial because it is able to identify regulatory T cells(More)
From Br IR Publ Fund H Conf CLINICAL PRESENTATION A 70-year-old man presented for evaluation of a solitary asymptomatic nodule on his right cheek. The tumor had appeared 2 months earlier and was rapidly growing (Fig 1). Clinical examination revealed a sharply demarcated, purple-red nodule of firm consistency, surrounded by an erythematous halo. Five months(More)
AIM Basal cell carcinoma (BCC) is the most common skin malignant neoplasm in humans. Its localization and its clinical-pathological aspects are fundamental for the treatment and the outcome of these tumors. We wanted to verify if different clinical-pathological subtypes of BCC may be present with different frequencies on single skin areas. METHODS Three(More)
Intralesional (incision) biopsy for melanoma diagnosis can be warranted for large lesions or for those lesions whose in-toto excision leads to cosmetic and/or functional impairment. However, this diagnostic approach carries a risk of underdiagnosis, if a clinicopathologic diagnostic approach is not implemented. As a rule, in large pigmented lesions from(More)
BACKGROUND Pigmented epitheliod melanocytoma (PEM) is a uncommon melanocytoma with unique histopathological features and possibly with a favourable prognosis, because, although sentinel lymph-node metastases may occur, in the great majority of cases described up to now there is no spread beyond regional lymph-nodes. The nature of PEM, its biologic behaviour(More)
S34 CLINICAL PRESENTATION An 82-year-old man with diabetes presented with a nonhealing, painless ulcer on his foot that had been present for 1 year (Fig 1, A). The lesion had been previously treated with topical therapy because of the clinical suspicion of diabetic ulcer. A nonhomogeneous, brownish hyperpigmentation was visible around the ulcer (Fig 1, B).(More)
BACKGROUND Biopsies and surgical excisions represent routine procedures in clinical settings dealing with skin cancer. OBJECTIVE To evaluate the impact of clinical examination, dermoscopy, reflectance confocal microscopy and digital monitoring on the decision to excise or biopsy a lesion in routine practice. METHODS Patients scheduled for biopsy or(More)
BACKGROUND Digital dermoscopy monitoring (DDM) is an effective strategy for melanoma detection. Two methods are currently employed. Short-term follow-up (STFU) for the evaluation of single, atypical lesions to detect subtle changes over a short period of time (3-6 months). Long-term follow-up (LTFU) is recommended for patients with multiple nevi. Although a(More)