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17-beta-Estradiol, at a concentration (100 ng/ml) approaching plasma levels found in pregnant women, inhibited the K+-evoked efflux of endogenous norepinephrine from superfused slices of rat hypothalamus. The same concentration of estradiol increased slightly the basal efflux of serotonin. Since estradiol crosses the blood-brain barrier with ease it is(More)
A popular conception about language development is that comprehension precedes production. Although this is certainly true during the earliest stages of phonological development, once a child possesses the basic articulatory skills required for imitation, it need not necessarily be the case. A child could produce a word without possessing the fully formed(More)
The authors describe three cases in which midazolam was successfully used in diagnostic hypnosedative interviews. A discussion comparing and contrasting midazolam to other intravenous hypnosedatives is presented. The authors suggest that midazolam is an effective agent for diagnostic hypnosedative interviews and may be preferable to other agents when(More)
Studies were done to determine the effects of ethanol on release of norepinephrine, dopamine and 5-hydroxytryptamine from nerve terminals in the central nervous system. Superfused slices of rat hypothalamus were used in these studies and endogenous amines in the superfusate were quantitated using HPLC with electrochemical detection. In these experiments(More)
The importance of high-affinity choline uptake in sustaining the synthesis of acetylcholine in isolated canine intrapulmonary airways was examined by using tissue bath techniques. Prolonged electrical stimulation of control airways caused contractions that decayed during the first few minutes of stimulation but eventually reached plateaus. In contrast,(More)
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