María de la O Rodríguez

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This paper introduces a four-degree-of-freedom parallel manipulator dedicated to pick-and-place. It has been developed with the goal of reaching very high speed. This paper shows that its architecture is particularly well adapted to high dynamics. Indeed, it is an evolution of Delta, H4 and 14 robots architectures: it keeps the advantages of these existing(More)
Nowadays an important research effort is devoted to lower mobility parallel manipulators. The existing solutions often suffer from parallel mechanisms drawbacks, i.e. small workspace and limited rotation capability. A new concept of parallel manipulators providing Schoen flies motions (motions of well-known SCARA robot) is introduced in this paper. The(More)
Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice are the most commonly used animals for modeling human staphylococcal infections. However a supra-physiologic S. aureus inoculum is required to establish gross murine skin pathology. Moreover, many staphylococcal factors, including Panton-Valentine leukocidin (PVL)(More)
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ. The treatment options are inadequate and reflect the fact that signaling targets in myofibroblasts are unknown. Here we identify the hyperactive Lyn signaling in myofibroblasts of(More)
An investigation was made into the effect of intracerebroventricular (i.c.v.) administration of antibodies to the amino-terminal portion 1-16 (MDSSTGPGNTSDCSDP) or the peptide sequence 208-216 (TKYRQGSID) of the cloned mu-opioid receptor (mu-OR) on morphine tolerance and dependence. Animals were rendered tolerant-dependent by subcutaneous (s.c.)(More)
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