María T Martínez-González

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Patent ductus arteriosus is frequent in premature babies. With an incidence of 1:2500-5000, it accounts for 9% to 12% of congenital heart disease. Several different drugs have been tried for closure of hemodynamically significant patent ductus arteriosus. The first to be used was indomethacin, with a success rate of 70% and a reopening rate of 35%; however,(More)
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