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Background K(+) channels of the TASK family are believed to participate in sensory transduction by chemoreceptor (glomus) cells of the carotid body (CB). However, studies on the systemic CB-mediated ventilatory response to hypoxia and hypercapnia in TASK1- and/or TASK3-deficient mice have yielded conflicting results. We have characterized the glomus cell(More)
2 Discovery of hemoglobin A expression outside of the erythroid cell lineage suggests that oxygen transport is the main but not the unique function of adult hemoglobin chains in mammals. The contribution of hemoglobin A to antioxidant defenses has been proposed in the territories where it is expressed. Catecholaminergic cells relay on an active oxidative(More)
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