María Soledad Díaz

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This work proposes a procedure for simultaneous parameters identifiability and estimation in metabolic networks in order to overcome difficulties associated with lack of experimental data and large number of parameters, a common scenario in the modeling of such systems. As case study, the complex real problem of parameters identifiability of the Escherichia(More)
Outline 9 9 Motivation Motivation 9 9 Objective Objective 9 9 Biological Biological and and biochemical biochemical determinations determinations 9 9 Global Global sensitivity sensitivity analysis analysis 9 9 Dynamic Dynamic parameter parameter estimation estimation problem problem 9 9 Optimal Optimal control control problem problem 9 9 Simultaneous(More)
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