María S. Millán

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PURPOSE To compare, as a function of pupil size, the through-focus performance and halo features of four diffractive intraocular lenses (IOLs). METHODS Three diffractive bifocal IOLs (ReSTOR +2.5 D SV25T0, Tecnis +2.75 D ZKB00, and AT LISA +3.75 D 809M) and a diffractive trifocal IOL (AT LISA tri +3.33 D, +1.66 D 839MP) were tested in vitro in a modified(More)
Recent versions of the International Organization for Standardization (ISO)-based model eye for intraocular lens testing include an artificial cornea whose spherical aberration is chosen to match the value of a human cornea. Aspheric lenses have been used as artificial corneas, but they are expensive and difficult to manufacture. This Letter demonstrates(More)
An antitumor agent thiocoraline is a thiodepsipeptide marine product derived from two Micromonospora sp. strains that inhibits protein synthesis by binding of its key 3-hydroxyquinaldic acid (3HQA) chromophores to duplex DNA. There are at least two potential pathways via which the 3HQA moiety could be biosynthesized from L-Trp. By biochemical(More)
Retinal imaging plays a key role in the diagnosis and management of ophthalmologic disorders, such as diabetic retinopathy, glaucoma, and age-related macular degeneration. Because of the acquisition process, retinal images often suffer from blurring and uneven illumination. This problem may seriously affect disease diagnosis and progression assessment. Here(More)
PURPOSE To determine the energy distribution between the distance and near images formed in a model eye by spherical and aspheric apodized diffractive multifocal intraocular lenses (IOLs). METHODS The IOL was inserted in a model eye with an artificial cornea with positive spherical aberration (SA) similar to that of the human cornea. The energy of the(More)
Gabor wavelets are applied to develop an unsupervised novelty method for defect detection and segmentation that is fully automatic and free of any adjustable parameter. The algorithm combines the Gabor analysis of the sample image with a statistical analysis of the wavelet coefficients corresponding to each detail. The statistical distribution of the(More)
A method to sharpen digital color images that takes viewing conditions and human vision models into consideration is described. The method combines the Laplacian of Gaussian (LoG) operator with spatial filters that approximate the contrast sensitivity functions of human visual systems. The sharpening operation is introduced in the opponent color space,(More)
Two descriptions of the image of a web structure, a convolution model and an additive model, in both the spatial and frequency domains, are combined in the design of a method to extract information about the fabric structure by image analysis. The method allows the extraction of the conventional and also the minimal weave repeats, their size in terms of(More)
The aged human eye is commonly affected by presbyopia, and therefore, it gradually loses its capability to form images of objects placed at different distances. Extended depth of focus (EDOF) imaging elements can overcome this inability, despite the introduction of a certain amount of aberration. This paper evaluates the EDOF imaging performance of the(More)