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Bipolar disorder (BD) is a recurrent, lifelong illness with high risks of disability and excess mortality. Despite many treatment options with demonstrated short-term efficacy, evidence concerning long-term treatment effectiveness in BD remains limited and the relative value of naturalistic studies versus randomized, controlled trials (RCTs) in its(More)
Early onset in bipolar disorder (BPD) has been associated with greater familial risk and unfavorable clinical outcomes. We pooled data from seven international centers to analyze the relationships of family history and symptomatic as well as functional measures of adult morbidity to onset age, or onset in childhood (age <12), adolescence (12-18), or(More)
INTRODUCTION Functional deficits are commonly observed in bipolar disorder after symptomatic remission. Social cognition deficits have also been reported, which could contribute to dysfunction in patients with bipolar disorder in remission. MATERIAL AND METHODS Twelve bipolar disorder patients in symptomatic remission (7 patients with bipolar disorder(More)
BACKGROUND Bipolar disorder presents with diverse clinical manifestations. Numerous investigators have sought to identify variables that may predict a more severe illness course. METHODS With the objective of studying the clinical characteristics of bipolar patients between South and North America, a comparison was performed between a sample from(More)
The purpose of our study was to assess the knowledge, social distance and perception of social discrimination towards persons with schizophrenia in the general adult population of Buenos Aires, Argentina. One thousand two-hundred fifty-four persons were surveyed at different neighborhoods of the city of Buenos Aires. Their knowledge about schizophrenia,(More)
INTRODUCTION Multiple psychosocial interventions for bipolar disorder have been proposed in recent years. Therefore, we consider that a critical review of empirically validated models would be useful. METHODS A review of the literature was conducted in Medline/PubMed for articles published during 2000-2010 that respond to the combination of "bipolar(More)
BACKGROUND Links between affective temperaments and folk culture have been infrequently explored systematically. Creativity and personality and temperament studies, conversely, have reported several associations. Tango is one of the most typical Argentinean folk dance-musical repertoires. The main purpose of this study is to compare affective temperaments(More)
BACKGROUND Since the current epidemiology of depression is not well documented in Latin America, we conducted a community-based survey study in Argentina. METHODS The Beck Depression Inventory (BDI) and a general health questionnaire were completed by 1335 adult participants, representing most of the neighborhoods of Buenos Aires. RESULTS Prevalence of(More)
INTRODUCTION Stigma surrounding mental illness is one of the main barriers for patients' reintegration into the community. Stigmatization is a social process characterized by different kinds of prejudices, stereotypes and discrimination. METHOD A review and synthesis of articles about mental illness stigmatization published in Medline in the past two(More)
BACKGROUND Bipolar disorder in its early phase results in a diagnostic and therapeutic challenge for the clinician. Individuals with bipolar disorder can be grouped according with their different clinical features such as the presence or absence of psychotic symptoms. Early illness detection and treatment is usually associated with a better prognosis. (More)