María F. Galindo

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  • Alexander Ternianov, José M Pérez-Ortiz, María E Solesio, María S García-Gutiérrez, Antonio Ortega-Álvaro, Francisco Navarrete +3 others
  • 2012
The role of CB2 cannabinoid receptors in the behavioral and neurochemical changes induced by intracaudate administration of 6-hydroxydopamine (6-OHDA) was evaluated. 6-OHDA (12 μg/4 μL) or its vehicle was injected in the caudate-putamen (CPu) of mice overexpressing the CB2 cannabinoid receptor (CB2xP) and wild type (WT) mice. Motor impairment, emotional(More)
Herein we report a method supported by a two-level Naive Bayes classifier to help and improve the automatic detection and counting of cells overexpressing GFP-chimeric proteins. This toll is frequently used as a reporter for the localization and the distribution pattern of a protein in a cell. This approximation requires, besides confocal microscopy, the(More)
Herein, we investigate whether the NADPH oxidase might be playing a key role in the degree of oxidative stress in the senescence-accelerated mouse prone-8 (SAM-P8). To this end, the activity and expression of the NADPH oxidase, the ratio of glutathione and glutathione disulfides (GSH/GSSG), and the levels of malonyl dialdehyde (MDA) and nitrotyrosine (NT)(More)
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