María Elena Hofmann Salcedo

Learn More
During the past 40 years, dengue haemorrhagic fever and dengue shock syndrome (DHF/DSS) have emerged in humans, with approximately 3 million cases reported and over 58 000 deaths. Dengue virus serotypes 1, 2 and 4 (DENV-1, -2 and -4) have been co-circulating in Venezuela for at least the past 10 years, causing minor or major outbreaks of dengue fever (DF)(More)
Virological surveillance of dengue viruses in Aedes aegypti populations constitutes a powerful tool for early prediction of dengue outbreaks. We have standardized a protocol for viral RNA extraction from individual and pools of mosquitoes that permits a sensitive detection of dengue virus without RNA degradation or PCR inhibition when we apply a semi-nested(More)
BACKGROUND Surgery is indicated in symptomatic flatfoot when conservative treatment fails to relieve the symptoms. Osteotomies appear to be the best choice for these painful feet. The purpose of this study was to compare the clinical and radiographic outcome of the calcaneo-cuboid-cuneiform osteotomies (triple C) and the calcaneal-lengthening osteotomy in(More)
This paper will describe a three-dimensional model used to generate knotted ribbons with minimal ribbon length, the ratio of the length of a ribbon to its width. This model treats ribbons as modified ropes and constructs them in three-dimensional space. It is shown that the ribbon length for all nontrivial framed unknots is 1, and that a lower bound for the(More)
ICDRG (International Contact Dermatitis Research Group) guidelines. The results are shown in Table 1. The positive reactions to wool alcohols, fragrance mix, colophony, and balsam of Peru had past relevance, but the positive reaction to black rubber mix did not. Six weeks later, we retested the patient with PG (0.5%, 1% and 2% aq.) showing positive results(More)
A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive(More)