María Cecilia Martínez

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In daily life, memories are intertwined events. Little is known about the mechanisms involved in their interactions. Using two hippocampus-dependent (spatial object recognition and contextual fear conditioning) and one hippocampus-independent (conditioned taste aversion) learning tasks, we show that in rats subjected to weak training protocols that induce(More)
Long-term memory (LTM) consolidation requires the synthesis of plasticity-related proteins (PRPs). In addition, we have shown recently that LTM formation also requires the setting of a "learning tag" able to capture those PRPs. Weak training, which results only in short-term memory, can set a tag to use PRPs derived from a temporal-spatial closely related(More)
Recently encoded information can be lost in the presence of new information, a process called 'retrograde interference'. Retrograde interference has been extensively described for more than a century; however, little is known about its underlying mechanisms. Different approaches agree on the need of the synthesis of plasticity related proteins (PRPs) to(More)
The aim of this work was to evaluate if the intraperitoneal administration of the natural compound hesperidin, in a sedative dose, and neo-hesperidin, a hesperidin structural analog that exerts minor sedative effect, were able to induce changes in intracellular signaling cascades in different areas of the brain. The systemic administration of hesperidin(More)
The synaptic tagging and capture theory (STC) was postulated by Frey and Morris in 1997 and provided a strong framework to explain how to achieve synaptic specificity and persistence of electrophysiological-induced plasticity changes. Ten years later, the same argument was applied on learning and memory models to explain the formation of long-term memories,(More)
Education is the most traditional means with formative effect on the human mind, learning and memory being its fundamental support. For this reason, it is essential to find different strategies to improve the studentś performance. Based on previous work, we hypothesized that a novel experience could exert an enhancing effect on learning and memory within(More)
Chatbots have been used in different scenarios for getting people interested in CS for decades. However, their potential for teaching basic concepts and their engaging effect has not been measured. In this paper we present a software platform called Chatbot designed to foster engagement while teaching basic CS concepts such as variables, conditionals and(More)
This paper describes a school intervention to teach fundamental Computer Science (CS) concepts to 3-11 year old students with a multilanguage robot programming platform (using drag and drop, Python and C++ languages) in Argentina. We analyze students' performance and learning process based on multiple choice test and classroom observations. Data show that(More)
Retroactive interference (RI) is a type of amnesia in which a new learning experience can impair the expression of a previous one. It has been studied in several types of memories for over a century. Here, we aimed to study in the long-term memory (LTM) formation of an object-in-context task, defined as the recognition of a familiar object in a context(More)
This paper describes an introductory Computer Science (CS) Professional Development (PD) course for K-12 teachers in Argentina that integrates pedagogical content knowledge and teacher classroom practice. We analyzed teachers' learning of what CS entails and the implementation of inquirybased programming lessons in their schools. Based on pre and post(More)