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Although Alzheimer's disease (AD) involves visual association cortex, previous studies have not systematically investigated complex visual disturbances in AD. We examined 30 community-based AD patients, 13 (43%) of whom had complex visual complaints, and compared them with 30 controls on 7 types of complex visual tasks. Despite preserved visual acuity and(More)
OBJECTIVE Considering the increasing use of complexity estimates in neuropsychiatric populations, a normative study is critical to define the 'normal' behaviour of brain oscillatory complexity across the life span. METHOD This study examines changes in resting-state magnetoencephalogram (MEG) complexity - quantified with the Lempel-Ziv complexity (LZC)(More)
Magnetoencephalography (MEG) allows the real-time recording of neural activity and oscillatory activity in distributed neural networks. We applied a non-linear complexity analysis to resting-state neural activity as measured using whole-head MEG. Recordings were obtained from 20 unmedicated patients with major depressive disorder and 19 matched healthy(More)
OBJECTIVE The neurodevelopmental-neurodegenerative debate is a basic issue in the field of the neuropathological basis of schizophrenia (SCH). Neurophysiological techniques have been scarcely involved in such debate, but nonlinear analysis methods may contribute to it. METHODS Fifteen patients (age range 23-42 years) matching DSM IV-TR criteria for SCH,(More)
Cognitive impairment is common in patients with schizophrenia, and even those with relatively preserved function perform worse than healthy volunteers (HVs) on attentional tasks. This is consistent with the hypothesis that connectivity - in the frontoparietal network (FPN) activated during attention - is disrupted in schizophrenia. We examined attentional(More)
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