María A. Ortiz

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Inhibition of the epidermal growth factor receptor (EGFR) tyrosine kinase activity by small molecules has proved effective for the treatment of cancer. To the best of our knowledge, the crystal structure of EGFR has been used for the first time to identify novel inhibitor chemotypes by docking-based in silico screening of a large virtual chemical library(More)
Hypochaeris leontodontoides is a rupicolous species endemic to the Atlas Mountains (Morocco), where it occurs in scattered populations. This study aims to understand the biogeographic structure of a high mountain species in a rather small area of NW Africa. We used Amplified Fragment Length Polymorphism (AFLP) to investigate the population structure and(More)
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