Manuela Andrioletti

Learn More
The embryotoxic potential of chlorpyrifos (CPF) and malathion (MTN), two organophosphorus insecticides (OPs), was evaluated by modified Frog Embryo Teratogenesis Assay-Xenopus (FETAX). CPF and MTN were not embryolethal even at the highest concentration tested (6000 microg/l), but both exhibited a powerful teratogenicity. The probit analysis of malformed(More)
It is estimated that over 80% of respirable particulate matter (PM10) in cities comes from road transport and that tire and brake wear are responsible for the 3–7% emission of it. Data on the indicators of environmental impact of tire debris (TD), originated from the tire abrasion on roads, are extremely scarce, even though TD contains chemicals (zinc and(More)
Data on the indicators of environmental impact of tire debris, originated from the tire abrasion on roads, are extremely scarce, while it is well known that tires may produce deleterious effects. Tire debris contains significant quantities of zinc (Zn) which may be released by tire rubber. We have used tire particles (TD) produced in laboratory from new(More)
Tire debris (TD) and its organic components were identified as a main source of PM10 atmospheric and water pollution. Because few data are available on the embryotoxic effects of TD organic components, the lethal and teratogenic potential of tire debris organic extract (TDOE) was evaluated using the frog embryo teratogenesis assay-Xenopus (FETAX), coupled(More)
The organogenesis and differentiation of striated tail musculature in Xenopus laevis (Amphibia, Anura) are an effective experimental model for studies on muscular dystrophy pathogenesis induced by oxidative stress [1]. Stage 37/38 embryo histopathological diagnosis reveals myoblasts with defects in contractile apparatus mainly localized at cell extremities(More)
Embryotoxic effects of Carbaryl (CB), a widely used carbamate insecticide, was evaluated by modified Frog Embryo Teratogenesis Assay-Xenopus (FETAX), coupled with a histopathological screening of the survived larvae. X. laevis embryos were exposed to 1, 2, 4, 8, 16 and 24 mg/L CB from stage 8 to stage 47. From an estimated LC50 of 20.28 mg/L and TC50 of(More)
  • 1