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We present here a three-dimensional FE model of the healthy human knee that included the main structures of the joint: bones, all the relevant ligaments and patellar tendon, menisci and articular cartilages. Bones were considered to be rigid, articular cartilage and menisci linearly elastic, isotropic and homogeneous and ligaments hyperelastic and(More)
BACKGROUND The anterior cruciate is the most frequent knee ligament to be totally disrupted. Surgical reconstruction of the anterior cruciate ligament is a common practice to treat the disability or chronical instability of knees due to anterior cruciate ligament insufficiency. Some of the factors that influence the success or failure of the anterior(More)
The goal of this work is to study the influence of the main geometrical parameters on the radial force of a self-expanding stent, and using them to advance towards a new design of a variable radial force stent to improve the interaction vessel-device. Using finite element simulations, a parametric analysis of a commercial stent model (Acculink, Abbot(More)
Nearly all soft tissues, among which the vascular tissue is included, present a certain degree of viscoelastic response. This behaviour may be attributed in part to fluid transport within the solid matrix, and to the friction between its fluid and solid constituents. After being preconditioned, the tissue displays highly repetitive behaviour, so that it can(More)
The passive mechanical properties of the ovine infrarenal vena cava are analysed in this paper. In vivo stretch from 15 venae was measured in order to get data from the physiological situation before harvesting the vessel. Vena cava strips (n=64) both in longitudinal and circumferential directions were cut and subjected to simple tension tests. Results(More)
Endothelial cells are key units in the regulatory biological process of blood vessels. They represent an interface to transmit variations on the fluid dynamic changes. They are able to adapt its cytoskeleton, by means of microtubules reorientation and F-actin reorganization, due to new mechanical environments. Moreover, they are responsible for initiating a(More)
BACKGROUND Many authors have suggested that the high levels of shear and tensile stresses that appear in the articular cartilage after meniscectomy are partly responsible for cartilage pathologies, such as osteoarthrosis. METHODS In this paper, we investigate the effect of meniscal tears and meniscectomies on the human knee joint. Solid models of the(More)
Plaque rupture plays a role in the majority of acute coronary syndromes. Rupture has usually been associated with stress concentrations, which are mainly affected by the plaque geometry and the tissue properties. The aim of this study is to evaluate the influence of morphology on the risk of plaque rupture, including the main geometrical factors, and to(More)
BACKGROUND A high tension in anterior cruciate ligament grafts affects both graft and knee functional performance. Clinical observations suggest that impingement of the graft against the posterior cruciate ligament might cause high graft tensions. Also, meniscal injury has been well documented in association with damage in the anterior cruciate ligament. (More)
Understanding the functional performance of vascular tissue is taking a rising importance due to the increasing impact of cardiovascular diseases in developed countries. Currently available medical imaging acquisition techniques, combined with computer modelling allow patient-specific simulations of customized geometries that may help in medical diagnosis(More)