Manuel Hofer

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The reversible phosphorylation of proteins on serine, threonine, and tyrosine residues is an important biological regulatory mechanism. In the context of genome integrity, signaling cascades driven by phosphorylation are crucial for the coordination and regulation of DNA repair. The two serine/threonine protein kinases ataxia telangiectasia-mutated (ATM)(More)
Man-made environments contain many weakly textured surfaces which are typically poorly modeled in sparse point reconstructions. Most notable, wiry structures such as fences, scaffolds, or power pylons are not contained at all. This paper presents a novel approach for generating line-based 3D models from image sequences. Initially, camera positions are(More)
Generating accurate 3D models for man-made environments can be a challenging task due to the presence of texture-less objects or wiry structures. Since traditional point-based 3D reconstruction approaches may fail to integrate these structures into the resulting point cloud, a different feature representation is necessary. We present a novel approach which(More)
Recovering 3D information from a single moving camera is a widely studied field in the area of computer vision (e.g. [1]). Most of these Structurefrom-Motion (SfM) approaches are based on so-called interest points (e.g. corners) in images, which can be accurately matched using powerful descriptors like SIFT [7]. Hence the output is usually a sparse 3D point(More)
Traditional Structure-from-Motion (SfM) approaches work well for richly textured scenes with a high number of distinctive feature points. Since man-made environments often contain textureless objects, the resulting point cloud suffers from a low density in corresponding scene parts. The missing 3D information heavily affects all kinds of subsequent(More)
We demonstrate simultaneous transverse dynamic force microscopy and molecular recognition imaging using tuning forks as piezoelectric sensors. Tapered aluminum-coated glass fibers were chemically functionalized with biotin and anti-lysozyme molecules and attached to one of the prongs of a 32kHz tuning fork. The lateral oscillation amplitude of the tuning(More)
Extracting 3D information from a moving camera is traditionally based on interest point detection and matching. This is especially challenging in the built environment, where the number of distinctive interest points is naturally limited. While common Structure-from-Motion (SfM) approaches usually manage to obtain the correct camera poses, the number of(More)
In this talk, we showcase our outcome of the ambitious 3D-PITOTI project, which involves a multidisciplinary team of over 30 scientists from across Europe. The project focuses on the 3D aspect of recording, storing, processing and visualizing prehistoric rock art in the UNESCO World Heritage site in Valcamonica, Italy. The rock art was pecked into open-air(More)
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