• Publications
  • Influence
Some special features of glyoxyl supports to immobilize proteins
Abstract This paper described that glyoxyl activated supports are only able to quantitatively immobilize proteins at alkaline pH values and using highly activated supports (otherwise, immobilizationExpand
  • 239
  • 4
General trend of lipase to self-assemble giving bimolecular aggregates greatly modifies the enzyme functionality.
Three microbial lipases (those from Candida rugosa, Humicola lanuginosa, and Mucor miehei) have been found to exhibit a tendency to form bimolecular aggregates in solution even at very low enzymeExpand
  • 143
  • 1
Nanotechniques in proteomics: protein microarrays and novel detection platforms.
The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging tasks of studying complexExpand
  • 68
  • 1
Immune System Dysfunction in the Elderly.
Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunityExpand
  • 60
  • 1
  • PDF
Relevance of Nck–CD3ε Interaction for T Cell Activation In Vivo
On TCR ligation, the adaptor Nck is recruited through its src homology 3.1 domain to a proline-rich sequence (PRS) in CD3ε. We have studied the relevance of this interaction for T cell activation inExpand
  • 28
  • 1
Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line.
Vanadium complexes were studied during recent years and considered as a representative of a new class of non-platinum metal antitumor agents in combination with their low toxicity. However, a fewExpand
  • 20
  • 1
Self-assembled protein arrays from an Ornithodoros moubata salivary gland expression library.
Protein interactions play a critical role in the regulation of many biological events and their study in a high-throughput format has become a key area of proteomic research. Nucleid AcidExpand
  • 28
  • 1
Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells.
Vanadium compounds were studied in recent years by considering them as a representative of a new class of non-platinum metal anticancer drugs. However, a few challenges still remain in the discoveryExpand
  • 14
  • 1
  • PDF
Screening of protein-protein and protein-DNA interactions using microarrays: applications in biomedicine.
In this report, we focus on two different array-based technologies that enable large-scale screening of protein interactions. First, protein arrays focus on the identification of protein-proteinExpand
  • 9
  • 1