Manuel Colmenero

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OBJECTIVE To analyze the effect on clinical outcomes of prophylactic positive end expiratory pressure in nonhypoxemic ventilated patients. DESIGN Multicenter randomized controlled clinical trial. SETTING One trauma and two general intensive care units in two university hospitals. PATIENTS One hundred thirty-one mechanically ventilated patients with(More)
PURPOSE OF REVIEW Accurate quantification of extravascular lung water is an important issue in the management of patients with pulmonary edema. The single transpulmonary thermal indicator method has been available since the late 1990s. Its simplicity and easy application make it clinically attractive. RECENT FINDINGS Several experimental studies have(More)
The influence of pineal gland function and of melatonin during pregnancy upon sexual maturation of female offspring in rats was examined. The following groups of Wistar rats were studied: (A) control, (B) melatonin treated (250 micrograms/100 g.b.w. per day) throughout pregnancy, and (c) pinealectomized (pin-x). Melatonin was injected subcutaneously 2 hr(More)
OBJECTIVES To analyze the use of noninvasive ventilation (NIV) in respiratory failure after extubation in patients after cardiac surgery, the factors associated with respiratory failure, and the need for reintubation. DESIGN Retrospective observational study. SETTING Intensive care unit in a university hospital. PARTICIPANTS Patients (n = 63) with(More)
PURPOSE OF REVIEW To provide an update of research findings on the mechanisms underlying respiratory complications after cardiac surgery, especially acute respiratory distress syndrome, transfusion-related lung injury and ventilation-associated pneumonia. The article will review some of the preventive and therapeutic measures that can be implemented to(More)
PURPOSE The incidence of acute respiratory distress syndrome (ARDS) was previously considered to be relatively low, at less than 10 cases per 100,000 inhabitants per year, but recent reports suggest a higher incidence, especially in elderly patients. The objective was to determine the incidence and mortality of ARDS in our setting, both overall and by age(More)
In order to determine the influence of physical training on menstrual disturbances in sportsgirls, the levels of luteinizing hormone (LH), follicle stimulating hormone (FSH) and melatonin have been studied in young athletes of track and field speciality using the Cooper test. Basal hormone levels and anthropometric data were also studied in age matched(More)
INTRODUCTION AND OBJECTIVES Risk of hospital death is one of the key factors considered by the clinical cardiologist when weighting indications for surgery. Risk estimation scales establish distinct levels of risk in quantitative terms. The aim of the present study was to investigate whether a low EuroSCORE value corresponds to low mortality in our setting.(More)
The radiological diagnostic approach of the thorax in the critically ill patient has traditionally been based on the anteroposterior chest X-ray. However, it is generally accepted that it has important limitations regarding its diagnostic accuracy of pleuro-pulmonary disease. The introduction of computed tomography largely solved this problem, but with the(More)
OBJECTIVE To compare the Acute Physiology, Age and Chronic Health Evaluation (APACHE) III with the Simplified Acute Physiology Score (SAPS II) in discriminating in-hospital mortality for intensive care unit (ICU) patients with acute myocardial infarction (AMI). DESIGN Prospective, observational, multicenter study. SETTING 70 Spanish ICUs. PATIENTS AND(More)