Manuel Carlos Ortega-Alvárez

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In 1996, Mexico started to register cases of childhood cancer. Here, we describe the incidence of cancer in children, residing in ten Mexican jurisdictions, who were treated by the Instituto Mexicano del Seguro Social (IMSS). New cases of childhood cancer, which were registered prospectively in nine principal Medical Centers of IMSS during the periods(More)
Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in public hospitals in Mexico City. Included in this(More)
There are very few studies that report the incidence of acute leukemias in children in Latin America. This work assesses the incidence of acute leukemias, between 1996 and 2000, in children from 0–14 years old who were attended at the Mexican Social Security Institute in Mexico City and in children from 0–11 years old in El Salvador. Design:(More)
Medical research has not been able to establish whether a father's occupational exposures are associated with the development of acute leukemia (AL) in their offspring. The studies conducted have weaknesses that have generated a misclassification of such exposure. Occupations and exposures to substances associated with childhood cancer are not very(More)
The objective of this population-based survey was to assess the peak age of incidence of B-cell precursor acute lymphoblastic leukemia (ALL) in children in Mexico City (MC). All patients were classified according to their immunophenotype, and only B-cell precursor and T-lineage were analyzed. Rates of incidence were calculated x10 children. Of the 364(More)
OBJECTIVE to determine the frequency and risk factors of non-compliance to oral metronidazole. STUDY DESIGN comparative cross-sectional survey. STUDY UNITS 111 patients who received oral metronidazole. SETTING CHARACTERISTICS: two medical units: one primary level unit and one secondary care unit of the Mexican Institute of Social Security. (More)
The causes of most leukemias are unknown; only a few exposures have been established as risk factors. Nowadays, the AL in children is considered as the result of the interaction of different environmental factors with the genetic susceptibility to the disease. In the first part of this review, the child's environmental factors were basically covered. Now,(More)
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