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Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury.
Rationale: There are controversial reports on applications of mesenchymal stromal cells (MSCs) in patients with acute respiratory distress syndrome (ARDS). Objectives: We hypothesized that lungExpand
Dual effects of human neutrophil peptides in a mouse model of pneumonia and ventilator-induced lung injury
BackgroundPneumonia is a major cause of high morbidity and mortality in critically illness, and frequently requires support with mechanical ventilation. The latter can lead to ventilator-induced lungExpand
Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells
Bacterial colonization of epithelial surfaces and subsequent transmigration across the mucosal barrier are essential for the development of infection. We hypothesized that the methyl-acceptingExpand
A rat model of acute respiratory distress syndrome induced by hydrochloric acid instillation combined with mechanical ventilation
Objective To establish a two-hit model of acute respiratory distress syndrom in rats with hydrochloric acid (HCl) instillation followed by mechanical ventilation. Methods SD rats were randomlyExpand