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  • Xavier Nissan, Lionel Larribère, +6 authors Christine Baldeschi
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2011 (First Publication: 19 August 2011)
  • Melanocytes are essential for skin homeostasis and protection, and their defects in humans lead to a wide array of diseases that are potentially extremely severe. To date, the analysis of molecularExpand
  • Xavier Nissan, Jerome Alexandre Denis, Manoubia Saidani, Gilles Lemaître, Marc Peschanski, Christine Baldeschi
  • Biology, Medicine
  • Developmental biology
  • 2011 (First Publication: 15 August 2011)
  • The molecular mechanisms controlling the differentiation of human basal keratinocyte stem cells towards the epidermis are well characterized, whereas the earliest process leading to the specificationExpand
  • Jennifer Allouche, Nathalia Bellon, +11 authors Christine Baldeschi
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2015 (First Publication: 6 July 2015)
  • Significance There are few suitable laboratory models for human pigmentation disease. Neurofibromatosis type 1 (NF1) is a common neurocutaneous disease whose initial symptoms in all patients areExpand
  • Alessandra Lo Cicero, M. Saidani, +8 authors X. Nissan
  • Medicine, Biology
  • Scientific Reports
  • 2018 (First Publication: 14 June 2018)
  • Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that leads to premature aging. In this study, we used induced pluripotent stem cells to investigate the hypopigmentationExpand